Injection Guide

Complete reference for injection techniques, needle selection, and site rotation.

Needle Gauge Reference

GaugeDiameterUse CaseInjection TypePain Level
18G 1.270 mm Drawing oil-based compounds from vial — too thick for injection Draw Only N/A
20G 0.908 mm Drawing thick oils (Test Undecanoate, high-concentration blends) Draw Only N/A
21G 0.819 mm Drawing standard oils — can inject into large muscles (glutes) if needed Draw / IM Moderate
23G 0.641 mm Standard IM injection — glutes, quads, delts. The workhorse gauge. IM Low-Moderate
25G 0.514 mm IM for delts, VG, pecs. Slightly slower push but less pip. IM Low
27G 0.413 mm SubQ injections (HGH, HCG, peptides). Shallow IM for delts. SubQ / Shallow IM Minimal
29G 0.337 mm Insulin pins — SubQ for HGH, HCG, BPC-157, TB-500, peptides. SubQ Nearly painless
30G–31G 0.311–0.260 mm Insulin pins — SubQ only. HGH, very thin water-based compounds. SubQ Painless

Needle Length by Site & Body Composition

SiteLean (<15% BF)Moderate (15-22%)Higher (>22%)
Ventrogluteal1 inch1.5 inch1.5 inch
Dorsogluteal1 inch1.5 inch1.5–2 inch
Vastus Lateralis (Quad)1 inch1 inch1.5 inch
Deltoid⅝ – 1 inch1 inch1 inch
Pectorals⅝ – 1 inch1 inch1 inch
Lats1 inch1 inch1.5 inch
SubQ (abdomen/love handles)½ inch½ inch½ – ⅝ inch

Injection Sites — Detailed

Click each site to expand the full technique walkthrough.

Recommended IM Max Volume: 3 mL

Why it's the go-to: The ventrogluteal site sits over the gluteus medius — a thick, well-vascularized muscle with minimal subcutaneous fat, very few major nerves, and no large blood vessels. Post-injection pain (PIP) is usually minimal compared to quads or dorsogluteal.

Locating the Site

  1. Lie on your side with the target hip facing up, or stand with weight shifted to the opposite leg.
  2. Place the heel of your palm on the greater trochanter (the bony bump at the top of your femur/hip).
  3. Point your index finger toward the anterior superior iliac spine (front hip bone point).
  4. Spread your middle finger posteriorly toward the iliac crest, creating a V-shape.
  5. The injection site is in the center of that V — the meatiest part of the gluteus medius.

Injection Technique

  1. Swab the area with an alcohol prep pad in a circular outward motion. Let it dry completely (30 seconds).
  2. Using a 23G–25G needle, 1–1.5" depending on body composition.
  3. Insert the needle at a 90° angle to the skin in one smooth, controlled motion.
  4. Aspiration (optional but recommended): pull back slightly on the plunger for 5–10 seconds. If blood fills the syringe, withdraw and relocate. No blood = you're in muscle.
  5. Inject slowly — about 10 seconds per mL. Rushing increases PIP.
  6. Once fully depressed, wait 10 seconds before withdrawing to prevent oil leaking from the injection tract (Z-track method: pull the skin to the side before inserting, release after withdrawing).
  7. Apply gentle pressure with a clean cotton ball. Do not massage unless using water-based compounds.

Tips

  • Rotate left and right VG each injection to prevent scar tissue buildup.
  • Warm the oil by holding the vial in your hands or placing it in warm (not hot) water for 2–3 minutes. Thinner oil = smoother injection = less PIP.
  • If you get sub-q leak (a lump near the surface), it's harmless — the oil just didn't deposit deep enough. Use a longer needle or more firmly apply Z-track next time.
Use Caution IM Max Volume: 4 mL

Overview: The dorsogluteal — the upper-outer quadrant of the buttock — was the traditional injection site for decades. It works, and the gluteus maximus can handle large volumes. The downside: the sciatic nerve runs through the area, and there's more subcutaneous fat here than VG, which means longer needles and higher risk of sub-q depot if you misjudge depth.

Locating the Site

  1. Mentally divide one buttock into four quadrants using the crease and midline.
  2. Target the upper-outer quadrant — specifically the upper-outer third of that quadrant.
  3. The injection point should be at least 2 inches from the midline and well above the gluteal fold.
  4. Palpate the area — it should feel like thick muscle, not bony or hollow.

Injection Technique

  1. Alcohol swab the area. Let dry.
  2. Use a 23G, 1.5" needle (or 2" if higher body fat).
  3. Insert at 90° — deep, smooth insertion. This is a thick muscle, you'll feel the needle punch through fascia then glide.
  4. Aspirate for 5–10 seconds. The gluteal region has more vasculature than VG.
  5. Inject slowly. 10 seconds per mL minimum.
  6. Apply Z-track method. Withdraw, apply pressure.

Why VG is Preferred Over This

  • Sciatic nerve risk — injecting too low or too medial can hit or irritate the sciatic nerve, causing shooting pain down the leg.
  • Thicker fat layer over the glute max means more chance of sub-q leak.
  • Harder to self-inject unless you're flexible or use a mirror.
IM Max Volume: 3 mL

Overview: The outer sweep of the quadricep — the vastus lateralis — is the easiest site to self-inject because you can see it, reach it while seated, and it's a large muscle. The trade-off: quads tend to have more PIP than glutes or delts, especially with higher-concentration oils or first-time users. There are also more nerve endings in the quad than the gluteal region.

Locating the Site

  1. Sit on a chair with your leg relaxed.
  2. Find the outer part of your thigh — from hip to knee, divide into three equal sections.
  3. Target the middle third, on the outer sweep (lateral side). Not the top of the quad — the SIDE.
  4. The sweet spot is about a hand's width above the knee and a hand's width below the hip, on the outer face.

Injection Technique

  1. Swab the site. Let dry.
  2. 23G–25G, 1" needle. Quads don't need length unless you carry significant fat on your legs.
  3. Insert at a 90° angle. The quad has multiple fascial layers — you may feel a slight "pop" as you pass through.
  4. Aspirate briefly. The femoral artery runs medially, not laterally, so risk is low if you're on the outer sweep.
  5. Inject SLOWLY. Quads are notorious for PIP if you push too fast. 15 seconds per mL.
  6. Withdraw, apply pressure. Light walking afterward can help disperse the oil and reduce next-day soreness.

Common Issues

  • Quad twitch: If the muscle visibly twitches during injection, you've likely nicked a nerve. It's not dangerous but it's uncomfortable. Withdraw slightly and redirect.
  • Leg buckling post-injection: Occasionally, a quad injection will cause temporary weakness. Walk it off — this resolves within minutes.
  • Virgin muscle PIP: First few quad injections are the worst. Stick with it — the site adapts after 3–4 pins.
IM Max Volume: 1.5 mL

Overview: Delts are a popular site for smaller-volume injections — TRT doses, HCG, or when rotating to give glutes and quads a break. The lateral head of the deltoid is easily accessible, has good blood flow, and absorbs oil well. Keep volumes under 1.5 mL though; the deltoid is a relatively small muscle and overfilling causes intense PIP and visible swelling.

Locating the Site

  1. Find the bony point at the top of your shoulder (the acromion process).
  2. Go about 2–3 finger widths below that point, on the lateral (outer) face of the arm.
  3. The injection site is the thickest part of the lateral deltoid — about midway between the shoulder cap and where the deltoid insertion meets the humerus.
  4. Flex the delt to visually confirm the muscle belly.

Injection Technique

  1. Swab. Let dry.
  2. 25G, ⅝"–1" needle. Delts are shallow — you don't need much length.
  3. Let the arm hang relaxed at your side. Insert at 90°.
  4. Inject slowly. Delts are sensitive — the slower the better.
  5. Withdraw, light pressure. No massage.
Advanced IM Max Volume: 1.5 mL

Overview: The pectoralis major is used by experienced users looking to add another rotation site. It's a large, flat muscle with good absorption. The risk profile is slightly higher because of proximity to the lungs (pneumothorax is extremely rare but theoretically possible with excessively long needles at wrong angles).

Locating the Site

  1. Target the upper-outer quadrant of the pec — roughly 2 inches below the collarbone and 2 inches from the sternum.
  2. Pinch the muscle. You should feel substantial meat between your fingers.
  3. Avoid injecting too medially (near sternum) or too low (near the nipple line).

Injection Technique

  1. Swab. Let dry.
  2. 25G, ⅝"–1" needle. Do NOT use a long needle here.
  3. Angle slightly — about 80° rather than straight 90° — pointing AWAY from the chest cavity.
  4. Insert into the muscle belly only. You should feel muscle, not rib.
  5. Inject slowly. Withdraw, light pressure.
IM Max Volume: 2 mL

Overview: The lats are a large, flat muscle on the mid-back. Surprisingly painless once you get the positioning right. Good for rotation, especially if you're running multiple compounds requiring frequent pins.

Locating the Site

  1. Reach behind you — target the area about 4 inches below the armpit, on the side of your back.
  2. The lat should feel like a thick sheet of muscle when you flex it (do a lat spread to confirm).
  3. Inject into the thickest part of the lat belly — not too close to the spine or ribs.

Injection Technique

  1. Swab. Let dry.
  2. 25G, 1" needle.
  3. Reach behind with your opposite hand, or have someone assist.
  4. Insert at 90°. The lat is surprisingly thick in muscular individuals.
  5. Inject slowly. Withdraw, light pressure.
Beginner Friendly SubQ Max Volume: 1 mL

Overview: Subcutaneous injections go into the fat layer beneath the skin — not into muscle. This is the standard route for HGH, HCG, insulin, BPC-157, TB-500, and most peptides. Uses insulin syringes (27G–31G), nearly painless, and doesn't require any special positioning.

Best Sites for SubQ

  • Abdomen: 2+ inches away from the navel, in the fatty tissue around the belly button. Most common site. Rotate left, right, above, below the navel.
  • Love handles: Pinch the fat at the side of your waist. Insert into the fold.
  • Upper thigh (front): Pinch fat on the top of the thigh. Good alternative if abdomen is overused.
  • Back of arm: Pinch the fat on the tricep area. Harder to self-administer but works.

SubQ Technique

  1. Swab the area with alcohol. Let dry.
  2. Use a 29G–31G insulin syringe with ½" needle.
  3. Pinch a fold of skin/fat between your thumb and index finger.
  4. Insert at 45° angle into the fat fold. If very lean, insert at a shallower angle to stay subcutaneous.
  5. Inject slowly. SubQ absorbs slower than IM — rushing can cause a painful lump.
  6. Release the pinch. Withdraw. No aspiration needed for SubQ.
  7. Apply light pressure if there's a drop of blood. A small welt is normal and absorbs within hours.

SubQ vs IM for Testosterone

Some TRT users inject testosterone subcutaneously in small doses (0.2–0.5 mL). Research shows comparable serum levels to IM with potentially steadier release. However, high-concentration oils (250+ mg/mL) or volumes above 0.5 mL can cause painful lumps that take days to absorb. SubQ test is viable for TRT-dose users; blast-dose users should stick to IM.

General Injection Tips

Sterility

  • Always use new, sealed needles for every injection.
  • Swap needles between drawing and injecting (draw with 18–21G, inject with 23–27G). Drawing dulls the tip.
  • Swab vial tops with alcohol before every draw.
  • Never reuse syringes or needles. Ever.
  • Wash hands thoroughly before handling supplies.

Managing PIP

  • Warm the oil before injection — hold the loaded syringe in your hand for 2–3 minutes or run warm water over the vial.
  • Inject slowly — fast plunger speed tears through muscle fibers.
  • Virgin muscle sites will have worse PIP for the first 3–5 injections. Push through it.
  • High-concentration brews (300+ mg/mL) cause more PIP. Consider diluting with sterile GSO or MCT oil.
  • Light activity post-injection (walking, light stretching) helps disperse the oil depot.

Recommended Rotation Schedule

For users pinning 2–3x per week (standard for most cycles):

Pin #SiteNotes
1Left VentroglutealMost comfortable, start here
2Right VentroglutealAlternate side
3Left DeltoidGood for smaller volumes
4Right DeltoidAlternate side
5Left Vastus LateralisUse if you need more sites
6Right Vastus LateralisAlternate side
RepeatBy the time you cycle back to site 1, it's had 2+ weeks to recover